,32,34,35,40,41,42,43 This delivery method, while convenient, is not feasible for translation to DMD patients, and such high dystrophin restoration in various skeletal muscles is likely due to intraperitoneal delivery introducing a high concentration of AAVs to the center of mass, particularly near the diaphragm and other proximal muscle groups, which is not currently possible with intravenous routes. The gene discussed is DMD; the disease is Duchenne muscular dystrophy.