Moving beyond heterotypic adhesion of platelets and WBCs to tumors, many cancer cells exhibit homotypic aggregation properties owing to the presence of various adhesion molecules (e.g., Thomsen-Friedenreich antigen, galectin-3, E-cadherin, and mucins) on their surface.336–338 By taking advantage of their unique self-recognition and self-adherence capabilities, cancer cell membranes have been frequently utilized to functionalize nanoparticles for efficient tumor-targeted drug delivery in recent years. Here, LGALS3 is linked to neoplasm.