Studies showed that high expression of eIF3f correlated with advanced gastric tumor stages and likelihood of recurrence[31] just like CRC, while eIF3f expression is significantly decreased in human pancreatic adenocarcinoma and melanoma,[32] and eIF3f inhibits tumor growth in cervical cancer model.[33] Yet, it is not clear how this discrepancy occurs. This evidence concerns the gene EIF3F and gastric neoplasm.