The combination of NCT‐503 and LGK‐974 was more efficient in suppressing tumor growth than NCT‐503 or LGK‐974 alone in the eIF3f high‐expressing PDX tumors, while the efficacy of these drugs on the eIF3f low‐expressing PDX tumors was compromised in terms of tumor volume and weights (Figure 7A,D). This evidence concerns the gene EIF3F and neoplasm.