Having the positive relevance of ZDHHC3 expression with the severity of NASH in mice model with ZDHHC3 loss‐of‐function experiments, ground on Rosaβgeo26 conditional and/or inducible transgenesis(hereunder named as RosaZdhhc3) (Figure S9a,b, Supporting Information). This evidence concerns the gene ZDHHC3 and metabolic dysfunction-associated steatohepatitis.