CD274 and neoplasm: Moreover, the immune escape mediated by upregulation of PD‐L1 expression in tumor cells due to increased IFN‐γ secretion after the PIT could be effectively blocked by BMS‐202, further amplifying the effect of PIT.[19] Thanks to the effective synergy of immunogenic pyroptosis induction and PD‐1/PD‐L1 blockade, YBS‐BMS NPs‐RKC exhibited potent tumor cell killing and antitumor immune activation abilities in in vitro and in vivo experiments, effectively inhibiting tumor growth in PCa subcutaneous tumor‐bearing mice model.