To explore the effect of SPJ treatment on cytokine expression, we used real‐time PCR and observed that viral infection led to increased expression of cytokines and chemokines, including IL‐6, IL‐1β, TNF‐α, IL‐10, IFN‐α, IFN‐β, and IFN‐γ, as well as CXCL‐2, CXCL‐10, CCL‐2, CCL‐3, and CCL‐5 (Fig. 6A–L). This evidence concerns the gene CCL2 and viral infectious disease.