There are only two articles that have been published on the DIAPH1 gene in Iran; one is the introduction of a rare case with homozygous DIAPH1 mutation leading to SCBMS,9 and the other surveyed the expression patterns of DIAPH1 and virulence genes of dental pathogenic bacteria in oral squamous cell carcinoma patients.10 The gene discussed is DIAPH1; the disease is oral cavity squamous cell carcinoma.