The most prevalent symptoms of affected individuals who harbored KCNQ3 mutation were ID (95.5%), DD (87%), speech disorder (70.9%), behavioral abnormality (58%), seizures (54.8%), strabismus (45.1%), hypotonia (35.5%), and gait disturbance (22.6%) (Table S2.3). This evidence concerns the gene KCNQ3 and dentin dysplasia.