PKD2 and autosomal dominant polycystic kidney disease: Using the NGS technique, Ranjzad et al reported a mutation rate of 88.9% and 11.1% in PKD1 and PKD2, respectively, in 18 Iranian ADPKD patients.23 Application of a custom designed Nimblegen chip, capturing the PKD1 and PKD2 genes, followed by NGS, all of mutations found in the study by Bitarafan and Gharshasbi were located in the PKD1 gene, with a lack of mutation in PKD2.