CRHR1 and major depressive disorder: Seven of the CRHR1-risk variants were in 2 LD blocks previously found to be linked to T2D and MDD in a prior analysis (unpublished results) and the same risk alleles of the variants (rs7209436, rs62057097, rs110402, and rs242941) in our current study were significantly linked and associated with the risk of T2D in the same dataset.