In addition, the cell-cell communications analysis showed that some interactions, involved in T cell recruitment, such as CXCL16-CXCR6; the formation of the immuno-suppressive microenvironment, such as LGALS9-HAVCR2, and ANXA1-FPR1; and promoting the proliferation and metastasis of tumor cells, were also detected between MRS1-tumor cells and MRS1-microenvironment cells. This evidence concerns the gene ANXA1 and neoplasm.