Hence, to analyze the connection between GLUT 1,2,3,4 and the immune infiltration of HNSCC, we used various databases (Oncomine, GEPIA, Kaplan–Meier, cBioPortal, GeneMANIA, and TIMER) and methods to determine the potential oncogenic values and immune infiltration of distinct GLUT family members in HNSCC patients. Here, SLC2A1 is linked to head and neck squamous cell carcinoma.