MYC and colorectal cancer: In addition, it’s increasingly evident that CCDC proteins are involved in the development and progression of cancers; for example, CCDC43 is an oncogenic factor in gastric cancer by promoting proliferation and metastasis [35], CCDC68 is a tumor suppressor of colorectal cancer through cell cycle arrest and growth inhibition [36], and CCDC106 suppresses lung adenocarcinoma by inducing c-Myc degradation [37].