As a subunit of laminin-332, which is responsible for normal epithelial cell adhesion, differentiation, and migration, LAMC2 is frequently overexpressed in various cancers including, lung cancer [12, 13, 32, 33], laryngeal cancer [34], gastric cancer [18], cholangiocarcinoma [25], thyroid carcinoma [11], and pancreatic ductal adenocarcinoma [35]. This evidence concerns the gene LAMC2 and cancer.