We subsequently determined the effect of targeting HSP90 (HSP90i) and HSP70 (HSP70i) as well as proteosome activity (MG132) on colony formation in 3 breast cancer cell lines, two pancreatic cell lines, 1 ovarian cancer cell line and 1 colorectal cell line in 2D culture (Fig. S7C). This evidence concerns the gene HSPA1A and breast carcinoma.