To investigate the molecular mechanisms of TMPO-AS1L in PCa bone metastasis more deeply, we took advantage of TMPO-AS1L-regulated transcriptome to carry out Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, which indicated that TMPO-AS1L might regulate the Wnt signaling pathway (Fig. S4C). Here, TMPO is linked to posterior cortical atrophy.