Silencing of DDX3X or CSNK2A1 in TMPO-AS1L overexpressing PCa cells attenuated the effect of TMPO-AS1L on Wnt/β-catenin activation and the phosphorylation of DVL2 (Figs. 6A, B and S8A–C). Here, DVL2 is linked to posterior cortical atrophy.