Interestingly, the expression of HBO1 protein in B-ALL cell lines (NALM-6, REH, and RS4;11) was significantly higher than that in T-ALL cell (Jurkat), AML cell (KG1a, NB4, MV4-11, and THP-1), and lymphoma cell lines (Raji, Daudi, Jeko-1, and NAMALWA) (Fig. 1C). This evidence concerns the gene KAT7 and acute myeloid leukemia.