EGFR and central nervous system cancer: Overexpression or mutation of EGFR frequently occurs in human GBM.[8, 9] To examine whether EGFR activation regulates CD47 expression, we treated a panel of human GBM cells, including U251, U87/EGFR, T98G, LN18, and GSC7‐11 cells, A549 lung cancer cell, SW480 colorectal cancer cell (Figure 2A), and mouse glioma cells, including GL261 and CT‐2A, (Figure S2A, Supporting Information) with EGF.