AICDA and cancer: 34,35,63 In contrast to most cancer types, where omikli and kataegis are predominately generated by APOBEC3 deaminases,64 in B cell malignancies, these clustered events are almost exclusively imprinted by the activity of AID.64 Further, the overall pattern of non-clustered mutations was very different than the ones of omikli or kataegis.