TLR4 and colitis: Consistent with our proposal, paeonol was reported to alleviate C. albicans-associated colitis induced by DSS in mice through suppressing dectin-1/NF-κB signaling in combination with TLR2 and TLR4 (Ge et al. 2021), while the antifungal drug fluconazole treatment could rescue the ulcerative colitis symptoms in mice (Leonardi et al. 2018).