We measured 6 common inflammatory cytokines (IFN-γ, IL-6, IL-10, IL-12p70, TNF-α and MCP-1) in supernatants from BM cell suspensions, which showed an initial increase of IFN-γ and MCP-1 levels during and shortly after infection, particularly evident in R2 mice infected with Hz-restricted parasite (Pb Δpm4-Δbp2) (Figure 7A). This evidence concerns the gene TNF and infection.