In keeping with the Gene Ontology assessment, GSEA revealed that FTO-lncAMLhighIRX3high AML samples expressed lower levels of genes upregulated in maturing myeloid cells by comparison with FTO-lncAML low IRX3high AML samples and higher levels of HOXA and HOXB genes (Figure 7G). This evidence concerns the gene FTO and acute myeloid leukemia.