MALAT1 and cancer: In addition, a recent meta-analysis showed that high MALAT1 expression levelsare associated with the PR+ tumor profile (95% CI 1.18–1.82; p= 0.0006) and, moreover, with decreased immune cell infiltration intothe tumor, which may be one of the reasons for the poor survival prognosis inbreast cancer patients with MALAT1 overexpression [71].