ESR1 and breast cancer: Finally, we would like to mention that Meseure et al.showed that both the expression level of the full-length MALAT1 transcript andthe expression level of the alternatively spliced MALAT1 transcript(∆sv-MALAT1) carrying two deletions can be used as prognostic factors:∆sv-MALAT1 hypoexpression in the tumor was observed in 19% of cases andwas positively correlated with a large tumor size, ER-negative, PR-negative,triple-negative subtypes of breast cancer, and a poor metastasis-free survivalchance [31].