MALAT1 and breast carcinoma: MALAT1 overexpression enhances cells’migration and invasion ability by binding to miR-1 and reducing the level ofCdc42, the protein involved in EMT [26].Furthermore, it was revealed using siMALAT1-mediated inhibition of MALAT1 and,conversely, by inserting the MALAT1 overexpression vector into a breast cancercell line that MALAT1 expression directly affects the expression of miR-124, amicroRNA associated with the suppression of breast cancer progression and thatMALAT1 overexpression suppresses the inhibitory effect of miR-124 on breasttumor growth, thus increasing its size [25].