A previous study has shown that the expression levels of Ki‐67 and p16INK4a, cell proliferation markers, are significantly higher in α‐HPV‐associated digital Bowen's disease/SCC as compared with HPV‐negative tumours, suggesting the presence of high‐risk α‐HPV in digital Bowen's disease/SCC is associated with high local invasiveness.7 The gene discussed is CDKN2A; the disease is neoplasm.