CHRM3 and cholinergic urticaria: In contrast, in the acetylcholine‐directly induced type which is also recognized as Cholinergic Urticaria with anhidrosis/hypohidrosis, eccrine sweat glands lack the expression of CHRM3 receptors thus the expression of CHRM3 is absent in anhidrotic areas and slightly present in hypohydrotic areas.