The results from metabolic pathway enrichment analysis of differential metabolites between GDM and HNPW groups showed that in positive ion mode (Figure 4F), 27 enriched metabolic pathways were significantly different between the two groups; the top three metabolic pathways with the largest differences between the two groups were intestinal immune network for IgA production (enriched with retinoate), small cell lung cancer (enriched with retinoate), and morphine addiction (enriched with two metabolites adenosine and dopamine). The gene discussed is CD79A; the disease is small cell lung carcinoma.