Similar to the results in the general population, Omega-3 intake resulted in a 27.1% risk reduction of incident liver disease in heterozygous carriers of the minor allele of PNPLA3 rs738409 (HR = 0.729; 95% CI: 0.602, 0.884; p = 1.0 × 10−3) (Table 3). Here, PNPLA3 is linked to liver disorder.