Among them, the widely studied MCL-1 inhibitors are BH3-mimics, including AZD5991, S63845, MIM1, etc. (Tron et al., 2018; Mallick et al., 2019; Moujalled et al., 2019; Wei et al., 2020), which have good effects on hematological tumors and multiple myeloma and have made great progress in combination with established therapies (Caenepeel et al., 2018). The gene discussed is MIMT1; the disease is AL amyloidosis.