SIRT1 and obesity due to melanocortin 4 receptor deficiency: Upregulation of miR-34a stress responsiveness after obesity may inhibit v-SNARE vesicle-associated membrane protein (VAMP) 2 expression in glucose transporter (GLUT) 4 vesicles via the nicotinamide phosphate nucleotidyl transferase (NAMPT)/nicotinic acid phosphate nucleotidyl transferase (NAPRT)/SIRT1/protein tyrosine phosphatase (PTP) 1B axis [87].