CLDN5 and infection: Figure 6C shows that all the genes tested were transiently but strongly decreased following 2 to 4 days of infection with the Beta variant (median decrease of TJP1: up to 83.6%; F11R: up to 82.1%; OCLN: up to 82.3%; CLDN5: up to 91.1% and CDH5: up to 93.3%) before a more moderate downregulation (TJP1, F11R, OCLN and CDH5) or upregulation (CLDN5) after 6 days of infection.