It turned out that mRNA (PNPLA3 and MVD), miRNA (hsa-miR-205-5p, hsa-miR-210-5p, has-and miR-144-5p), and miRNA-associated lncRNAs and circRNAs play key roles in the initiation and progression of PCOS. Here, PNPLA3 is linked to polycystic ovary syndrome.