Among the genes we identified through coexpression of three datasets, PNPLA3, MVD, MMP9, oncostatin M (OSM), LCK, triggering receptor expressed on myeloid cells 1 (TREM1), FADS2, proprotein convertase subtilisin/kexin type 9 (PCSK9), and C3 are involved in lipid metabolism and ovarian dysfunction. The gene discussed is C3; the disease is ovarian dysfunction.