IFNG and neoplasm: It also displayed a trend to decrease the abundance of CD3+ T cells in the ileum and colon (Extended Data Fig. 2b) and significantly repressed the expression of Ifng, which encodes interferon (IFN)-γ, a key tumour immune surveillance cytokine predominantly produced by activated lymphocytes16, in all segments of the intestine of MR diet-fed Apcmin+/− mice (Fig. 2b).