Further analysis of total CD45+ immune cells in the small intestine of diet-fed tumour-free B6 donor mice (B6-CTRL and B6-MR) and chow-fed faecal recipient Apcmin+/− mice (Apc-FT-CTRL and Apc-FT-MR) by single-cell RNA-sequencing (scRNA-seq) showed that small-intestinal CD45+ immune cells could be categorized into seven functional groups (with 26 clusters) based on the expression patterns of known marker genes (Extended Data Fig. 6a,b and Supplementary Tables 5 and 6, a). The gene discussed is APC; the disease is neoplasm.