RNH1 and cancer: We found a significant increase in the promoter methylation level of RNH1 in tissues of 15 cancer types (BLCA, BRCA, CESC, COAD, ESCA, HNSC, KIRC, KIRP, LUAD, LUSC, SARC, PRAD, THCA, PAAD, and THCA) compared to normal tissues (Fig. 1C).