CD4 and bladder transitional cell carcinoma: We discovered a significant positive correlation between RNH1 expression in BLCA and the infiltration levels of 28 TIICs, especially activated dendritic cells, central memory CD4 T cells, natural killer cells, natural killer (NK) T cells, plasmacytoid dendritic cells, regulatory T cells, T follicular helper cell, and macrophages (Fig. 5A).