Noteworthy, the observed anxiolytic phenotype cannot be attributed to ataxia since the average total distance moved was similar in the control groups of SCA2 and WT mice (Fig. 4E), and the median related to the total distance was even greater in SCA2 mice compared to their WT littermates, although it did not reach the statistically significant difference (p = 0.14). The gene discussed is ATXN2; the disease is spinocerebellar ataxia type 2.