Analysis of RNA-seq data showed that Ctnnb1 mRNA was upregulated in prostate tumors of Pb-T2-ERG;Trp53pcR172H/- mice, but not in prostatic tissues of Pb-T2-ERG and Trp53pcR172H/- single mutant mice relative to WT mice, and this observation was further confirmed by RT-qPCR (Fig. 4a, b, c). This evidence concerns the gene ERG and prostate neoplasm.