The CTNNB1 mRNA expression level was much higher in p53-mutated PCa cell lines VCaP (p53 R248W) and DU145 (p53 R223L/V274F) compared to p53-WT or p53-null cell lines including C4-2, LNCaP, PC-3 and 22Rv1 (Supplementary Fig. 6e). Here, CTNNB1 is linked to posterior cortical atrophy.