Moreover, MAPK14 expression increased gradually with the progress of STAD, MAPK14 expression in Stage3 and Stage4 STAD tumor tissues was significantly higher than that in normal samples, and MAPK14 expression in Stage4 STAD tumor tissues was remarkably higher than that in stage2 STAD tumor tissues, P < 0.05 (Fig. 4D). This evidence concerns the gene MAPK14 and gastric adenocarcinoma.