Unlike findings in the lung adenocarcinoma cell line A549 and B-cell acute lymphoblastic leukemia Nalm6, G9a and GLP are not involved in GR/HP1γ interactions in TNBC cells, highlighting that GR transcription factors regulate functions in a tissue-dependent manner through the recruitment of different sets of coregulators (Poulard et al, 2017, 2019). The gene discussed is EHMT2; the disease is acute lymphoblastic leukemia.