BNC2 and neoplasm: We report seemingly contradictory findings in that BNC2 is generally expressed at lower levels in tumours compared with normal tissue (Figs 8 and S8); however, high BNC2 expression in tumours corresponds to more advanced disease, poorer prognosis, and the classification of increased types of lower-survival tumours (metaplastic and claudin-low) (Figs 8, S10, and S11).