Table 3 shows that TCF‐1 negativity (HR: 0.408; 95% CI: 0.188–0.886; p = 0.023), CD8 negativity (HR: 0.331; 95% CI: 0.111–0.986; p = 0.047), TIM‐3 expression positivity (HR: 1.680; 95% CI: 1.079–2.615; p = 0.022), LAG‐3 expression positivity (HR: 1.637; 95% CI: 1.038–2.581; p = 0.034), PD‐1 expression positivity (HR: 1.977; 95% CI: 1.264–3.094; p = 0.003), pathological stage (HR: 3.049; 95% CI: 1.670–5.568; p < 0.002), and tumor grade 3 (HR: 6.770; 95% CI: 1.261–36.344; p = 0.026) were independent prognostic factors due to a worsening RFS. Here, CD8A is linked to neoplasm.