Identification of other proteins soon followed; Fused in Sarcoma (FUS) and TAR DNA-binding protein-43 (TDP-43), both linked to amyotrophic lateral sclerosis (ALS), α-Synuclein (αSyn) in Parkinson’s disease (PD), multiple systemic atrophy (MSA) and Lewy body dementia (LBD), and huntingtin protein in Huntington disease, among many others. Here, HTT is linked to multiple system atrophy.