An example of k-means clusteringis found in the2019 conference paper by Syarofina et al., in which the authors utilize k-means clustering, along with a variety of clustering evaluators,to create a model capable of discovering molecules that inhibit dipeptidylpeptidase-4 (DPP-IV).92 DPP-IV is a significanttarget for the treatment of type 2 diabetes mellitus, and the discoveryof potential inhibitors for DPP-IV is an important drug developmentgoal. This evidence concerns the gene DPP4 and diabetes mellitus.