Cutaneous melanoma was the primary in 270 patients (84.9%), 171 (53.8%) had BRAF/NRAS wild-type variants, 113 (35.5%) had resected stage IIIB, and 124 (39.0%) had resected stage IIIC melanomas (AJCC Cancer Staging Manual, version 8). The gene discussed is NRAS; the disease is cutaneous melanoma.