Nonetheless, some potential biomarkers were noticed in the serum of patients with periodontitis, such as resistin [73], C-reactive protein [74], visfatin [75], oncostatin M [76], chemokine CXCL10 [77], and proprotein convertase subtilisin/kexin type 9 (PCSK9) [78]. The gene discussed is CRP; the disease is periodontitis.