SETBP1 and melanoma: Further analysis based on samples from the TCGA cohort revealed significantly reduced SETBP1 expression in the SETBP1 mutant subgroup in both melanoma (Wilcoxon rank-sum test P = 0.034; Supplementary Figure 9C) and NSCLC (Wilcoxon rank-sum test P = 0.008; Supplementary Figure 9D).