Survival analysis indicated that there was no significant survival difference between SETBP1 two groups (multivariate Cox P = 0.143; Supplementary Figure 10A) in melanoma; however, a significantly preferable prognosis was observed in SETBP1-MUT NSCLC patients (multivariate Cox P = 0.043; Supplementary Figure 10B). The gene discussed is SETBP1; the disease is non-small cell lung carcinoma.