Interestingly, the HCC TAN clusters [27] can be identified in scRNAseq analysis of other cancers including gastric cancer [28], pancreatic ductal adenocarcinoma (PDAC) [29] and non-small cell lung cancer (NSCLC) [30] by comparison of most differentially expressed marker genes, with the exception of APOA2+ lipid-associated TANs which so far appear to be specific to the liver. The gene discussed is APOA2; the disease is non-small cell lung carcinoma.