uPAR is commonly upregulated and expressed on the leading edge of migratory leukocytes and can also be cleaved and released into the blood as soluble uPAR (suPAR; Dai et al, 2006; Viswanathan et al, 2009; Fleetwood et al, 2014; Yu et al, 2019; Yu & Liu, 2019; D'Alonzo et al, 2020; Acanfora et al, 2021; Arnold et al, 2021; de Bruina et al, 2021; Guo et al, 2021; Keskinidou et al, 2021; Zuo et al, 2021; The PHOSP‐COVID Collaborative Group, 2022) and has been reported as a marker for severe COVID‐19 with higher mortality. This evidence concerns the gene PLAUR and COVID-19.