Introduction of miRIDIAN miR224-3p into Capan1 cells (Figures 5A, B) and U87MG cells (Figures 5C, D) increased apoptosis and cleaved caspase-3 levels while suppressing eIF2〈 phosphorylation in response to TG, Tun, or CDDP in both cancer cells. This evidence concerns the gene CASP3 and cancer.