For example, miR-224 has a tumor-promoting effect in nonsmall cell lung cancer (8, 9), pancreatic cancer (10), and cervical cancer (11) via targeting of homeobox D10 (HOXD10) (8, 9), androgen receptors (8, 9), thioredoxin-interacting protein (TXNIP) (8, 9), and Ras-association domain family 8 (RASSF8) (8, 9). This evidence concerns the gene TXNIP and familial pancreatic carcinoma.