CD274 and non-small cell lung carcinoma: After the occurrence of resistance to first-line EGFR-TKIs in the 123 NSCLC patients, univariate analysis was performed of their age, gender, smoking history, whether or not receiving immunotherapy, driver mutation type, ECOG score, PD-L1 TPS expression, neutrophil count (NEUT), lymphocyte count (LYM), monocyte count (MON), platelet count (PLT) and inflammation-related factors in serum, and neutrophil-lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and platelet to lymphocyte ratio (PLR).