The Evan's blue MPE/blood ratio and Ki67+ area in pleural tumors were decreased in the IL-10−/− group (Figure 1(c), right two panels), indicating that IL-10 absence suppressed the development of MPEs by reducing vascular permeability and inhibiting tumor angiogenesis and proliferation, consistent with the findings of previous studies [13, 14]. This evidence concerns the gene MKI67 and neoplasm.