LAMB2 and Alzheimer disease: Giuliani et al. (2019) reported that cortical microvessel density, as evaluated by laminin immunostaining on coronal slices, was higher in 5-month-old Tg2576 mice, compared with age-matched WT, but was lower at 27 months in Tg2576 mice. We also reported an overall increase in vascular density with age in the 3xTg-AD mouse model using vessel painting (Jullienne et al., 2022a).